Biochemistry
**Biochemistry** is one of the foundational subjects in **first-year MBBS**, focusing on the chemical processes in the human body. It helps in understanding **metabolism, enzymatic reactions, and molecular biology**. ### **Main Lessons in Biochemistry** #### **1. Biomolecules** - Carbohydrates (glucose, fructose, glycogen) - Proteins (amino acids, peptides, structural proteins) - Lipids (fatty acids, triglycerides, phospholipids) - Nucleic acids (DNA, RNA, nucleotides) #### **2. Enzymes & Metabolism** - Enzyme structure, function, and regulation - Enzyme kinetics (Michaelis-Menten equation) - Coenzymes and cofactors - Metabolism of carbohydrates, proteins, and fats - Glycolysis, Krebs cycle, and oxidative phosphorylation - Electron transport chain and ATP production #### **3. Vitamins & Minerals** - Water-soluble vitamins (B-complex, C) - Fat-soluble vitamins (A, D, E, K) - Role of minerals (iron, calcium, zinc, magnesium) #### **4. Molecular Biology & Genetics** - DNA replication, transcription, translation - Genetic code and mutations - Recombinant DNA technology - PCR, gene therapy, and applications in medicine #### **5. Hormonal Biochemistry** - Insulin and glucagon in glucose metabolism - Thyroid hormones and metabolism - Adrenal hormones (cortisol, adrenaline) #### **6. Clinical Biochemistry** - Liver function tests (LFTs) - Kidney function tests (KFTs) - Blood glucose regulation and diabetes - Lipid profile and cardiovascular diseases #### **7. Acid-Base Balance & Buffers** - pH regulation in the body - Buffer systems (bicarbonate, phosphate, protein buffers) - Respiratory and renal compensation
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